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Properties of substance:

folic acid



skc-file

Group of substances:

organic

Physical appearance:

yellow needles crystals

Empirical formula (Hill's system for organic substances):

C19H19N7O6

Molar/atomic mass: 441.41

Melting point (°C):

250

Decomposition temperature (°C):

250

CAS №: 59-30-3

Solubility (g/100 g of solvent):

1-butanol: sparingly soluble [Ref.]
acetic acid: very soluble [Ref.]
acetone: insoluble [Ref.]
benzene: insoluble [Ref.]
chloroform: insoluble [Ref.]
diethyl ether: insoluble [Ref.]
ethanol: sparingly soluble [Ref.]
methanol: sparingly soluble [Ref.]
phenol: soluble [Ref.]
pyridine: very soluble [Ref.]
water: 0.00016 (25°C) [Ref.]

Dissociation:

pKa (1) = 8.26 (25°C, water)

LD50 (mg/kg):

10000 (mice, oral)
282 (mice, intravenous)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-278
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 925-927
  3. The Merck Index. - 15th ed. - Royal Society of Chemistry, 2013. - pp. 774-775
  4. Справочник химика. - 2 изд., Т. 2. - Л.-М.: Химия, 1964. - pp. 1058-1059 [Russian]
  5. Химическая энциклопедия. - Т. 5. - М.: Советская энциклопедия, 1999. - pp. 111-112 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru